Gly-His-Lys tripeptide · Copper Peptide GHK-Cu
≥99% HPLC per independent batch · the measured value of each batch is on its COA
Refrigerated at 2–8°C in our warehouse · lyophilized and stable during shipping
Receive it in 1 to 3 business days
If it is lost in transit, at no cost
| Molecular class | Copper tripeptide |
| Sequence | Gly-His-Lys complexed with Cu(II) |
| Formula | C14H22CuN6O4 |
| Molecular weight | 403.94 g/mol |
| CAS | 89030-95-5 |
| Purity | 99% HPLC (guaranteed minimum; the measured value of each batch is on its COA) |
| Storage | -20°C lyophilized · 2-8°C reconstituted |
| Presentation | Price | Per mg |
|---|---|---|
| 50 mg | $800 MXN | $16.00 MXN |
| 100 mg | $1,200 MXN | $12.00 MXN mejor precio |
You can buy GHK-Cu in Mexico for research at NeoPeptidos. GHK-Cu is an endogenous copper tripeptide (Glycine-Histidine-Lysine bound to Cu²⁺) found naturally in human plasma, saliva and urine. Its levels decline with age and it has been widely investigated in collagen synthesis, wound healing, skin repair and antioxidant effects.
See the full technical sheet: mechanism, evidence and regulatory status ↓
The following research areas have been studied in preclinical models (in vitro and in vivo in animals). This information is for scientific reference only.
Chemical identity, studied mechanism, quality of the available evidence and regulatory status. Reference material; you do not need to read it to buy.
Resulting concentration depending on the bacteriostatic water you add, and its equivalent in units on a U-100 insulin syringe (100 IU = 1 mL). For this vial, 2 mL is recommended.
| BAC water | Concentration | 250 mcg | 500 mcg | 1000 mcg |
|---|---|---|---|---|
| 1 mL | 50,000 mcg/mL | 0.5 IU (0.01 mL) | 1 IU (0.01 mL) | 2 IU (0.02 mL) |
| 2 mL recommended | 25,000 mcg/mL | 1 IU (0.01 mL) | 2 IU (0.02 mL) | 4 IU (0.04 mL) |
| 3 mL | 16,666.67 mcg/mL | 1.5 IU (0.02 mL) | 3 IU (0.03 mL) | 6 IU (0.06 mL) |
| 5 mL | 10,000 mcg/mL | 2.5 IU (0.03 mL) | 5 IU (0.05 mL) | 10 IU (0.1 mL) |
The reference masses are volumetric calculation values for laboratory work, not an administration schedule. Material for scientific research use only.
Resulting concentration depending on the bacteriostatic water you add, and its equivalent in units on a U-100 insulin syringe (100 IU = 1 mL). For this vial, 3 mL is recommended.
| BAC water | Concentration | 250 mcg | 500 mcg | 1000 mcg |
|---|---|---|---|---|
| 1 mL | 100,000 mcg/mL | 0.25 IU (0 mL) | 0.5 IU (0.01 mL) | 1 IU (0.01 mL) |
| 2 mL | 50,000 mcg/mL | 0.5 IU (0.01 mL) | 1 IU (0.01 mL) | 2 IU (0.02 mL) |
| 3 mL recommended | 33,333.33 mcg/mL | 0.75 IU (0.01 mL) | 1.5 IU (0.02 mL) | 3 IU (0.03 mL) |
| 5 mL | 20,000 mcg/mL | 1.25 IU (0.01 mL) | 2.5 IU (0.03 mL) | 5 IU (0.05 mL) |
The reference masses are volumetric calculation values for laboratory work, not an administration schedule. Material for scientific research use only.
Need a different amount? Use the reconstitution calculator or see the full table by vial.
Current status: Mixed status depending on the route: accepted by the FDA for compounding in topical application, flagged for the injectable route.
In Mexico, a research peptide is sold as a laboratory reagent (RUO, research use only). It is not a medicine: it has no COFEPRIS sanitary registration for human or veterinary use, it is not dispensed in pharmacies and it does not require a prescription, precisely because it is not sold to be administered to people. RUO labeling is not a commercial technicality; it is the product's regulatory category and defines what can and cannot legally be done with it. Since it is a domestic shipment, the order does not go through customs and is not subject to import procedures.
Regulatory framework reviewed in August 2026. See the full regulatory timeline, with the dates of each FDA decision between 2023 and 2026.
Compounds in the same category, with what sets each one apart and its entry price. Mechanism and cost are compared, not efficacy: there are no human trials that allow them to be ranked by outcome.
| Compound | What sets it apart | From |
|---|---|---|
| GHK-Cu este producto | Gly-His-Lys tripeptide · Copper Peptide GHK-Cu | $800 ($16/mg) |
| Epitalon | Pineal regulatory tetrapeptide · Synthetic Epithalamin | $2,520 ($50/mg) |
| MOTS-c | Mitochondrial peptide · Mitochondrial Open Reading Frame 12S c | $1,100 ($110/mg) |
| Thymalin (agotado) | Thymic peptide extract · Immunomodulator | $1,100 ($110/mg) |
Comparativa detallada: GHK-Cu vs BPC-157 →
GHK-Cu is a tripeptide with the sequence glycyl-L-histidyl-L-lysine complexed with divalent copper. It is one of the best-characterized peptides in skin biology, and one of the few in the catalog with an established cosmetic use and decades of commercial formulation behind it.
It was identified in human plasma by Loren Pickart in the 1970s, in the context of research on age-associated plasma factors. Its plasma concentration declines markedly with age, an observation that sparked much of the later interest in the compound.
In terms of chemical identity, it is classified as Copper tripeptide, its CAS number is 89030-95-5, its molecular weight is 403.94 g/mol. These identifiers are what allow the material received to be checked against the batch Certificate of Analysis.
Also known as: Copper peptide · Gly-His-Lys-Cu tripeptide.
Copper is not an inert companion: the GHK tripeptide has a high affinity for divalent copper and the complex acts as a physiological carrier of the ion. Much of the described activity depends on that delivery of copper to copper-dependent enzymes, including lysyl oxidase, which is involved in the cross-linking of collagen and elastin.
In dermal models, modulation of the expression of type I collagen, elastin, glycosaminoglycans and matrix metalloproteinases has been described, that is, of both the synthesis and the controlled degradation of the extracellular matrix. That dual effect is what is described as remodeling, and it distinguishes it from a simple synthesis stimulus.
Route used in the studies: Mainly topical (cosmetic); SC in research. It is given for documentation purposes, to interpret the literature; it is not an instruction for use.
Within this catalog, GHK-Cu is one of the compounds with the most established topical dermatological evidence, with literature on wound healing and skin quality parameters. It is also the only case with a split regulatory status: in the FDA update of September 29, 2023 it was placed in Category 1 with limitations for topical use, while its injectable routes were flagged in Category 2.
That route-based distinction is exactly the nuance worth keeping in mind. Topical evidence does not automatically transfer to the injectable route, which is the one the FDA flagged and for which the data are much more limited.
The material in this catalog is a research reagent, not a finished cosmetic or a medicine. A commercial cosmetic with GHK-Cu is a formulated product, with validated stability, preservation and concentration, which is something else.
Reference: Pickart's work on GHK-Cu; mostly topical.
The following lines appear in the preclinical literature. They are listed for scientific reference only: they are not indications, efficacy claims or suggestions for use.
| Compound | Main difference |
|---|---|
| AHK-Cu | A related copper tripeptide, with literature focused mainly on the hair follicle. Less characterized than GHK-Cu. |
| Mezcla GLOW | It combines GHK-Cu with BPC-157 and TB-500 in one vial. Since they are three different molecules, it has no single chemical identity. |
The vial is delivered lyophilized, that is, as a dry powder obtained by freeze-drying. In that form it is stable and does not require a cold chain during transport: shipping does not compromise the material. On receipt, it is kept refrigerated between 2 and 8 °C, protected from light.
For the GHK-Cu strengths, a reference reconstitution would be: el vial de 50 mg with 2 mL of bacteriostatic water queda a 25 mg/mL; el vial de 100 mg with 3 mL of bacteriostatic water queda a 33.33 mg/mL. The volume is not fixed — more water gives a more dilute solution with a larger measuring margin; less water concentrates it — and the choice depends on the working protocol.
The diluent is added slowly along the wall of the vial, never directly onto the powder, and left to rest for five to ten minutes. The vial is swirled gently until fully dissolved; shaking it hard subjects the peptide to mechanical stress that can denature it. Once reconstituted, it is kept refrigerated and is not frozen.
Bacteriostatic water contains 0.9% benzyl alcohol as a preservative, which allows multiple draws from the same vial. Plain sterile water has no preservative and is only suitable for immediate use. Signs of degradation to watch for: cloudy solution, visible particles, change in color or odor.
Because the agency evaluated the routes separately. In the September 29, 2023 update, topical use was placed in Category 1 with limitations, while the injectable routes were flagged in Category 2. Topical evidence is not automatically extrapolated to the injectable route.
Yes, it is an essential part of the compound. The tripeptide acts as a carrier of the copper ion to enzymes that depend on it, such as lysyl oxidase, which is involved in the cross-linking of collagen and elastin. Without copper, the GHK tripeptide is not the same compound.
No. It is sold exclusively as a research-use-only (RUO) reagent, labeled as not fit for human consumption. It has no COFEPRIS sanitary registration and no approval from any other agency for human or veterinary use.
Every batch comes with a Certificate of Analysis issued by an independent laboratory, with the HPLC chromatogram, the purity percentage, the batch number and the date of analysis. It is included in the price and you can download it from the product page and from your account.
Shipping is express, 1 to 3 business days depending on the area, with a tracking number, to all 32 states. Since it is a domestic shipment sent from within Mexico, it does not go through customs: there are no holds or import procedures.
Lessons from the free certification that explain GHK-Cu and its scientific context:
This compound has no reviews of its own yet. Below you can see what customers say about other products in the catalog: each card shows which one it refers to.
Super bien muy recomedado este laboratorio y llegan en 2 dias 🙏🏻 gracias seguire comprando con ellos
Es mi segunda vez que pido y estoy más que convencido de la excelente calidad y servicio de su equipo... ampliamente recomendables
Empaque excelente, Recibir tu pedido con agua Bac3ml es lo mejor. Entrega en 3 días max.
Me sorprendió la atención y la presentación, llegó a tiempo y muy bien empacado y con su BAC water, absolutamente recomendables y también tiene su guía de preparación y uso que te llega con dos QR en tu paquete
Excelente servicio, muy amables, siempre he recibido mis productos en tiempo y forma, llegan muy bien protegidos y el producto me ha funcionado de maravilla
el servicio desde el primer contacto excelente el envio rapido y todo a la perfecccion los peptidos una maravilla
Excelente servicio, muy amables, muy el paquete llegó en tiempo y forma, muy bien empaquetado y producto de calidad.
Es la 3a vez que compro y todo va bien ! Los empaques de lujo y el seguimiento igual ! Éxitos
Excelente servicio, muy seguro, el péptico llegó perfectamente empacado, llego en el tiempo indicado
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