Body Protection Compound · Gastric pentadecapeptide
≥99% HPLC per independent batch · the measured value of each batch is on its COA
Refrigerated at 2–8°C in our warehouse · lyophilized and stable during shipping
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| Molecular class | Synthetic pentadecapeptide |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV) |
| Formula | C62H98N16O22 |
| Molecular weight | 1419.53 g/mol |
| CAS | 137525-51-0 |
| Purity | 99% HPLC (guaranteed minimum; the measured value of each batch is on its COA) |
| Storage | -20°C lyophilized · 2-8°C reconstituted |
| Presentation | Price | Per mg |
|---|---|---|
| 10 mg | $1,200 MXN | $120.00 MXN |
| 20 mg | $2,000 MXN | $100.00 MXN mejor precio |
You can buy BPC-157 in Mexico for research at NeoPeptidos. BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid pentadecapeptide derived from a gastric protective protein found in human gastric juice. It is one of the research peptides with the largest number of published preclinical studies, especially in tissue repair models.
See the full technical sheet: mechanism, evidence and regulatory status ↓
The following research areas have been studied in preclinical models (in vitro and in vivo in animals). This information is for scientific reference only.
Chemical identity, studied mechanism, quality of the available evidence and regulatory status. Reference material; you do not need to read it to buy.
Resulting concentration depending on the bacteriostatic water you add, and its equivalent in units on a U-100 insulin syringe (100 IU = 1 mL). For this vial, 1 mL is recommended.
| BAC water | Concentration | 250 mcg | 500 mcg | 1000 mcg |
|---|---|---|---|---|
| 1 mL recommended | 10,000 mcg/mL | 2.5 IU (0.03 mL) | 5 IU (0.05 mL) | 10 IU (0.1 mL) |
| 2 mL | 5,000 mcg/mL | 5 IU (0.05 mL) | 10 IU (0.1 mL) | 20 IU (0.2 mL) |
| 3 mL | 3,333.33 mcg/mL | 7.5 IU (0.08 mL) | 15 IU (0.15 mL) | 30 IU (0.3 mL) |
| 5 mL | 2,000 mcg/mL | 12.5 IU (0.13 mL) | 25 IU (0.25 mL) | 50 IU (0.5 mL) |
The reference masses are volumetric calculation values for laboratory work, not an administration schedule. Material for scientific research use only.
Resulting concentration depending on the bacteriostatic water you add, and its equivalent in units on a U-100 insulin syringe (100 IU = 1 mL). For this vial, 2 mL is recommended.
| BAC water | Concentration | 250 mcg | 500 mcg | 1000 mcg |
|---|---|---|---|---|
| 1 mL | 20,000 mcg/mL | 1.25 IU (0.01 mL) | 2.5 IU (0.03 mL) | 5 IU (0.05 mL) |
| 2 mL recommended | 10,000 mcg/mL | 2.5 IU (0.03 mL) | 5 IU (0.05 mL) | 10 IU (0.1 mL) |
| 3 mL | 6,666.67 mcg/mL | 3.75 IU (0.04 mL) | 7.5 IU (0.08 mL) | 15 IU (0.15 mL) |
| 5 mL | 4,000 mcg/mL | 6.25 IU (0.06 mL) | 12.5 IU (0.13 mL) | 25 IU (0.25 mL) |
The reference masses are volumetric calculation values for laboratory work, not an administration schedule. Material for scientific research use only.
Need a different amount? Use the reconstitution calculator or see the full table by vial.
Current status: No regulatory approval in any country. Under active FDA evaluation.
In Mexico, a research peptide is sold as a laboratory reagent (RUO, research use only). It is not a medicine: it has no COFEPRIS sanitary registration for human or veterinary use, it is not dispensed in pharmacies and it does not require a prescription, precisely because it is not sold to be administered to people. RUO labeling is not a commercial technicality; it is the product's regulatory category and defines what can and cannot legally be done with it. Since it is a domestic shipment, the order does not go through customs and is not subject to import procedures.
The published literature is broad in preclinical models and comes largely from the Croatian group that originally described the peptide. There are no published phase III clinical trials supporting therapeutic use in humans.
Regulatory framework reviewed in August 2026. See the full regulatory timeline, with the dates of each FDA decision between 2023 and 2026.
Compounds in the same category, with what sets each one apart and its entry price. Mechanism and cost are compared, not efficacy: there are no human trials that allow them to be ranked by outcome.
| Compound | What sets it apart | From |
|---|---|---|
| BPC-157 este producto | Body Protection Compound · Gastric pentadecapeptide | $1,200 ($120/mg) |
| TB-500 | Thymosin Beta-4 fragment · Tβ4 Acetate | $1,100 ($110/mg) |
| BPC + TB Combo | Synergistic repair stack · Wolverine Stack | $2,000 ($100/mg) |
| GLOW | BPC-157 + GHK-Cu + TB-500 · Triple repair stack | $2,800 ($40/mg) |
Comparativa detallada: BPC-157 vs TB-500 → · GHK-Cu vs BPC-157 → · KPV vs BPC-157 →
BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide, that is, a chain of fifteen amino acids, with the sequence GEPPPGKPADDAGLV. It corresponds to a partial fragment of a protective protein found in human gastric juice, and it is probably the tissue-repair peptide with the most accumulated preclinical literature.
It was characterized in the early 1990s by the group of Predrag Sikirić and Sven Seiwerth at the University of Zagreb, Croatia, as part of a line of work on gastric cytoprotection. Its most distinctive chemical trait is stability: it has no disulfide bridges or post-translational modifications, and it withstands the acidic environment of the stomach without degrading, something uncommon among peptides that made it possible to study it both systemically and orally in animal models.
In terms of chemical identity, it is classified as Synthetic pentadecapeptide, its CAS number is 137525-51-0, its molecular weight is 1419.53 g/mol. These identifiers are what allow the material received to be checked against the batch Certificate of Analysis.
Also known as: Body Protection Compound · gastric pentadecapeptide.
The best-documented pathway is the angiogenic one. In 2017, Hsieh and colleagues reported in Journal of Molecular Medicine that BPC-157 increases the expression of vascular endothelial growth factor receptor 2 (VEGFR2) and promotes its cellular internalization, activating the VEGFR2-Akt-eNOS pathway in cascade. The relevant methodological detail is that the effect was observed on the receptor VEGFR2 and not on the ligand VEGF-A, and that it was blocked by inhibiting endocytosis with dynasore, which suggests that receptor internalization is part of the mechanism rather than a side effect.
A later study by the same group, published in Scientific Reports in 2020, described a second related route: BPC-157 promotes the phosphorylation of Src and caveolin-1, which releases endothelial nitric oxide synthase (eNOS) from its inhibitory binding to caveolin-1 and increases nitric oxide production. In isolated rat aorta it produced concentration-dependent vasodilation that disappeared when the endothelium was removed and was inhibited by L-NAME or hemoglobin, confirming that the effect is mediated by nitric oxide.
In tendon injury models, involvement of the FAK-paxillin pathway in fibroblasts has also been described, a pathway involved in cell migration and adhesion to the extracellular matrix. Taken together, the literature does not describe a single receptor: it describes a compound that modulates several converging pathways in vascular and tissue repair, which has been proposed as the explanation for its appearance in models of very different tissues.
Route used in the studies: Subcutaneous (SC) or intramuscular near the area studied. It is given for documentation purposes, to interpret the literature; it is not an instruction for use.
Precision matters here, because this is where most pages about BPC-157 exaggerate. The preclinical base is genuinely broad: more than two hundred published studies over three decades, on intestine, tendon, ligament, muscle, bone, cornea, blood vessels and the nervous system, with an unusual consistency of results.
That same consistency is the point the critical literature highlights. A 2025 review in Pharmaceuticals (Józwiak and colleagues) documented that more than 80% of the records indexed under “BPC 157” are linked to the original Zagreb group, and that the experiments routinely use single doses, with no data on higher, repeated or prolonged exposures. Sikirić's group published a reply defending the compound's profile, and there is a counter-reply: it is an open, documented scientific debate, not a forum controversy.
As for human data, the short answer is that there are none. A 2025 systematic review in HSS Journal (Vasireddi, Hahamyan, Salata and colleagues) synthesized 36 studies published between 1993 and June 2024 —35 preclinical animal studies and one uncontrolled chart review— and documented zero completed controlled clinical trials, a plasma half-life of under 30 minutes and an absence of clinical safety data in humans.
There is also a risk consideration that the literature raises explicitly and that should not be omitted: a compound that increases the expression and activation of VEGFR2 acts on the same receptor that drives tumor vascularization. The 2025 reviews note that there are no in vivo data showing that BPC-157 inhibits tumor progression, and they warn about its pro-angiogenic profile in the presence of subclinical or undiagnosed neoplasms. It is an open question, not resolved experimentally.
The following lines appear in the preclinical literature. They are listed for scientific reference only: they are not indications, efficacy claims or suggestions for use.
BPC-157 is frequently studied alongside other repair compounds, and the difference between them is not one of potency but of mechanism and scope of action.
| Compound | Main difference |
|---|---|
| TB-500 | It acts by sequestering G-actin and reorganizing the cytoskeleton, with systemic distribution. BPC-157 acts on angiogenic signaling and its literature focuses on local effects, mainly gastrointestinal and tendon-related. |
| GHK-Cu | It is a copper-complexed tripeptide, studied mainly in skin and extracellular matrix remodeling, with broad topical application. BPC-157 does not provide copper and is not studied as a cosmetic. |
| Mezcla BPC-157 + TB-500 | It combines both in one vial. Since they are two different molecules, the blend has no single chemical identity: it does not have its own CAS number, formula or sequence. |
The vial is delivered lyophilized, that is, as a dry powder obtained by freeze-drying. In that form it is stable and does not require a cold chain during transport: shipping does not compromise the material. On receipt, it is kept refrigerated between 2 and 8 °C, protected from light.
For the BPC-157 strengths, a reference reconstitution would be: el vial de 10 mg with 1 mL of bacteriostatic water queda a 10 mg/mL; el vial de 20 mg with 2 mL of bacteriostatic water queda a 10 mg/mL. The volume is not fixed — more water gives a more dilute solution with a larger measuring margin; less water concentrates it — and the choice depends on the working protocol.
The diluent is added slowly along the wall of the vial, never directly onto the powder, and left to rest for five to ten minutes. The vial is swirled gently until fully dissolved; shaking it hard subjects the peptide to mechanical stress that can denature it. Once reconstituted, it is kept refrigerated and is not frozen.
Bacteriostatic water contains 0.9% benzyl alcohol as a preservative, which allows multiple draws from the same vial. Plain sterile water has no preservative and is only suitable for immediate use. Signs of degradation to watch for: cloudy solution, visible particles, change in color or odor.
No. No regulatory agency has approved it as a medicine. In the United States it was placed in Category 2 of the 503A list on September 29, 2023, removed from that category in April 2026 and reviewed by the FDA advisory committee in July 2026, but none of those steps amounts to an approval.
Because it contains no disulfide bridges or post-translational modifications, which are the points where other peptides usually degrade. That stability made it possible to study it orally in animal models, something unfeasible with labile peptides such as insulin or native GLP-1.
There are no completed controlled clinical trials. The 2025 systematic review in HSS Journal identified 35 preclinical animal studies and a single chart review without a control group, between 1993 and June 2024.
No. It is sold exclusively as a research-use-only (RUO) reagent, labeled as not fit for human consumption. It has no COFEPRIS sanitary registration and no approval from any other agency for human or veterinary use.
Every batch comes with a Certificate of Analysis issued by an independent laboratory, with the HPLC chromatogram, the purity percentage, the batch number and the date of analysis. It is included in the price and you can download it from the product page and from your account.
Shipping is express, 1 to 3 business days depending on the area, with a tracking number, to all 32 states. Since it is a domestic shipment sent from within Mexico, it does not go through customs: there are no holds or import procedures.
Lessons from the free certification that explain BPC-157 and its scientific context:
Excelente servicio, muy amables, siempre he recibido mis productos en tiempo y forma, llegan muy bien protegidos y el producto me ha funcionado de maravilla
Excelente servicio, muy amables, muy el paquete llegó en tiempo y forma, muy bien empaquetado y producto de calidad.
Excelente servicio, muy seguro, el péptico llegó perfectamente empacado, llego en el tiempo indicado
Super bien muy recomedado este laboratorio y llegan en 2 dias 🙏🏻 gracias seguire comprando con ellos
Es mi segunda vez que pido y estoy más que convencido de la excelente calidad y servicio de su equipo... ampliamente recomendables
Empaque excelente, Recibir tu pedido con agua Bac3ml es lo mejor. Entrega en 3 días max.
Me sorprendió la atención y la presentación, llegó a tiempo y muy bien empacado y con su BAC water, absolutamente recomendables y también tiene su guía de preparación y uso que te llega con dos QR en tu paquete
el servicio desde el primer contacto excelente el envio rapido y todo a la perfecccion los peptidos una maravilla
Es la 3a vez que compro y todo va bien ! Los empaques de lujo y el seguimiento igual ! Éxitos
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