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06
TB-500 (Thymosin β4)
Tissue repair- Class: synthetic fragment of the active domain of thymosin β4.
- Target / mechanism: G-actin binding and regulation of the cytoskeleton → cell migration, angiogenesis and repair (including cardiac models).
- Key pharmacology: good tissue diffusion; often studied in combination with BPC-157.
- Context: preclinical research on recovery and regeneration.
07
GHK-Cu
Dermal · repair- Class: tripeptide (Gly-His-Lys) complexed with copper(II).
- Target / mechanism: extracellular matrix remodeling (collagen, elastin, metalloproteinases) and broad modulation of gene expression toward a regenerative profile.
- Key pharmacology: high affinity for copper; studied by topical and systemic routes.
- Context: wound healing, dermal health and aesthetics.
08
Ipamorelin
Somatotropic · GHRP- Class: GH secretagogue, ghrelin mimetic (GHS-R).
- Target / mechanism: selective stimulation of GH release with minimal effect on cortisol and prolactin.
- Key pharmacology: "clean" profile because of its selectivity; short-acting.
- Context: frequently combined with CJC-1295 for GHRH+GHRP synergy.
09
CJC-1295
Somatotropic · GHRH- Class: long-acting GHRH analog.
- Target / mechanism: GHRH receptor in the pituitary; stimulation of the GH pulse.
- Key pharmacology: form without DAC (resistant to DPP-4, medium action) and with DAC (albumin binding, prolonged action).
- Context: canonical combination with ipamorelin.
10
Tesamorelin
Somatotropic · GHRH- Class: stabilized GHRH analog.
- Target / mechanism: GHRH receptor; stimulation of the GH/IGF-1 axis with a characteristic impact on fat distribution (visceral fat).
- Key pharmacology: the GHRH analog with the most established formal clinical development.
- Context: the clinical reference among GHRH analogs.
Catalogue compounds mentioned in this lesson
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