Peptide comparison
Both are melanocyte-stimulating hormone analogs investigated in pigmentation, but they differ in receptor selectivity, which defines their effect profile.
Compare mechanism, class, receptors and evidence. All compounds are offered with ≥99% purity verified by HPLC and a batch COA.
| Melanotan-1 | Melanotan-2 | |
|---|---|---|
| Class | Melanocortin agonist (afamelanotide) | Melanocortin agonist |
| Selectividad | More selective for MC1R | Menos selectivo (varios subtipos) |
| Foco | Melanogenesis (pigmentation) | Pigmentation with a broader effect profile |
| Perfil | More "selective and clean" | More potent, broader effects |
Melanotan-1 (afamelanotide) is more selective for the MC1R receptor, central to melanogenesis. Melanotan-2 is a less selective agonist that activates several melanocortin receptor subtypes, which broadens its effect profile. The pharmacological lesson is subtype selectivity: small sequence differences redirect the molecule within the same family.
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Melanotan-1 (afamelanotide) is more selective for the MC1R receptor (pigmentation); Melanotan-2 is less selective and activates several melanocortin subtypes, with a broader effect profile.
Purity ≥99% verificada por HPLC and batch COA.
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