MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA (in the 12S region). It belongs to a relatively new class known as mitochondria-derived peptides. It is studied in research on metabolic homeostasis. NeoPeptidos offers it with ≥99% HPLC purity, for research use.
Technical profile
| Product | MOTS-c |
|---|---|
| CAS | 1627580-64-6 |
| Molecular formula | C₇₅H₁₂₃N₂₁O₂₃S₂ |
| Molecular weight | 1722.06 Da |
| Sequence | MRWQEMGYIFYPRKLR (16 aa) |
| Purity | 99% HPLC |
| Presentation | Lyophilized vial; bacteriostatic water included |
| Use | For scientific research use only |
What is MOTS-c?
Unlike most peptides, which come from nuclear DNA, MOTS-c is encoded by the mitochondrial genome. This places it among the so-called mitochondria-derived peptides (MDPs), of great interest in the study of communication between the mitochondria and the rest of the cell.
Research context
Research on MOTS-c has focused on glucose metabolism, energy homeostasis and the response to exercise in preclinical models.
These studies are investigational in nature and do not constitute claims of efficacy in humans. MOTS-c is offered for research use only.
Handling and reconstitution
See the reconstitution guide and the storage guide.
Quality and traceability
≥99% purity by HPLC and batch COA. See quality control.
🔬 Updated on June 2, 2026 · Reviewed by the NeoPeptidos team · Content for research purposes (RUO).