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The newest frontier studies peptides linked to cellular aging:
- Epitalon: a tetrapeptide (Ala-Glu-Asp-Gly) derived from pineal epithalamin, investigated for its relationship with telomerase activity and the regulation of telomere length, as well as effects on the circadian rhythm of melatonin.
- MOTS-c: a peptide encoded by the mitochondrial genome ("mitochondrial-derived peptide"), studied for its role in metabolic homeostasis, AMPK activation and cellular stress signaling.
- SS-31 (elamipretide): binds to cardiolipin in the inner mitochondrial membrane, stabilizing crista architecture and the efficiency of the electron transport chain.
- Humanin: another mitochondrial peptide with research in cytoprotection.
Outside the strictly peptide category but conceptually adjacent, NAD⁺ and its precursors participate in energy metabolism and sirtuin pathways. The biology of longevity is a young, fast-moving field; the professional value lies in reading its literature —mostly preclinical or early-phase— distinguishing robust physiological signal from premature enthusiasm.
Catalogue compounds mentioned in this lesson
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Go to the quiz →Educational content for scientific purposes. It distinguishes preclinical from clinical evidence and is not medical advice, diagnosis or a recommendation for use. NeoPeptidos products are sold labelled for research use only (RUO).